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ACAD10
Pathway / Platelet adhesion & activation

ACAD10

ACAD10protein

ACAD10 controls platelet mitochondrial homeostasis and activation state, modulating the thrombotic response to vascular injury.

Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencemedium
RationaleRegulates platelet mitophagy and activation during thrombosis.
Druggability
DruggableYes
Known drugs / candidates0
Small-molecule tractableYes
Antibody tractableNo
EnsemblENSG00000111271

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)

Human genetic evidence

1
GWAS associations
Traits: myocardial infarction

Literature evidence(1)