Soluble CD40 ligand

Type I vs Type II discrimination

Assay & specimen

Human genetic evidence

Literature evidence(59)

• Biomarkers of Thrombosis in ST-Segment Elevation Myocardial Infarction: A Substudy of the ATOLL Trial Comparing Enoxaparin Versus Unfractionated Heparin.
  American journal of cardiovascular drugs : drugs, devices, and other interventions · 2018 · PMID 30144017 · doi
• Novel biomarkers of cardiovascular disease: Applications in clinical practice.
  Critical reviews in clinical laboratory sciences · 2018 · PMID 30457415 · doi
• Biomarkers of endothelial activation and thrombosis in tunnel construction workers exposed to airborne contaminants.
  International archives of occupational and environmental health · 2017 · PMID 28124139 · doi
• Comparison of diverse platelet activation markers as indicators for left atrial thrombus in atrial fibrillation.
  Platelets · 2017 · PMID 28287031 · doi
• Plant-based Food Cyanidin-3-Glucoside Modulates Human Platelet Glycoprotein VI Signaling and Inhibits Platelet Activation and Thrombus Formation.
  The Journal of nutrition · 2017 · PMID 28855423 · doi
• Platelet activation at the onset of human endotoxemia is undetectable in vivo.
  Platelets · 2016 · PMID 26764560 · doi
• Integrity(®) bare-metal coronary stent-induced platelet and endothelial cell activation results in a higher risk of restenosis compared to Xience(®) everolimus-eluting stents in stable angina patients.
  Platelets · 2016 · PMID 26765134 · doi
• Comparison of the influence of ticagrelor and clopidogrel on inflammatory biomarkers and vascular endothelial function for patients with ST-segment elevation myocardial infarction receiving emergency percutaneous coronary intervention: study protocol for a randomized controlled trial.
  Trials · 2016 · PMID 26865043 · doi
• Thrombus Aspirated from Patients with ST-Elevation Myocardial Infarction: Association between 3-Nitrotyrosine and Inflammatory Markers - Insights from ARTERIA Study.
  International journal of medical sciences · 2016 · PMID 27429583 · doi
• Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase β, and Not Via CD40 and IκB Kinase α.
  Arteriosclerosis, thrombosis, and vascular biology · 2015 · PMID 25908768 · doi
• Platelet-specific markers are associated with monocyte-platelet aggregate formation and thrombin generation potential in advanced atherosclerosis.
  Thrombosis and haemostasis · 2015 · PMID 26467184 · doi
• Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction.
  Thrombosis research · 2015 · PMID 26475405 · doi
• Aspirin resistance in adult patients after Fontan surgery.
  International journal of cardiology · 2014 · PMID 25479533 · doi
• Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome.
  Atherosclerosis · 2013 · PMID 23664202 · doi
• Inflammatory and thrombotic markers in patients with ST-elevation myocardial infarction treated with thrombolysis and early PCI: a NORDISTEMI substudy.
  Thrombosis research · 2012 · PMID 22607887 · doi
• Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases.
  PloS one · 2012 · PMID 22624015 · doi
• Composition of coronary thrombus in acute myocardial infarction.
  Journal of the American College of Cardiology · 2011 · PMID 21414532 · doi
• Platelet and monocyte activity markers and mediators of inflammation in Takotsubo cardiomyopathy.
  Heart and vessels · 2011 · PMID 21416113 · doi
• Day-night variations in endothelial dysfunction markers and haemostatic factors in sleep apnoea.
  The European respiratory journal · 2011 · PMID 21852330 · doi
• From atherosclerosis to acute coronary syndromes: the role of soluble CD40 ligand.
  Trends in cardiovascular medicine · 2010 · PMID 21742271 · doi
• Platelet turnover, coagulation factors, and soluble markers of platelet and endothelial activation in essential thrombocythemia: relationship with thrombosis occurrence and JAK2 V617F allele burden.
  American journal of hematology · 2009 · PMID 19105233 · doi
• Markers of inflammation, thrombosis and endothelial activation correlate with carotid IMT regression in stable coronary disease after atorvastatin treatment.
  Nutrition, metabolism, and cardiovascular diseases : NMCD · 2009 · PMID 19171469 · doi
• Bivalirudin reduces platelet and monocyte activation after elective percutaneous coronary intervention.
  Thrombosis and haemostasis · 2009 · PMID 19190819
• Biomarkers in cardiovascular medicine.
  Revista espanola de cardiologia · 2009 · PMID 19480764 · doi
• The CD40/CD40 ligand system: linking inflammation with atherothrombosis.
  Journal of the American College of Cardiology · 2009 · PMID 19679244 · doi
• Inflammatory systemic biomarkers in setting acute coronary syndromes--effects of the diurnal variation.
  Current drug targets · 2009 · PMID 19860643 · doi
• Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome.
  Diabetes care · 2008 · PMID 18487475 · doi
• Characterization of the human atheroma plaque secretome by proteomic analysis.
  Methods in molecular biology (Clifton, N.J.) · 2007 · PMID 17172685 · doi
• Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease.
  Vascular medicine (London, England) · 2007 · PMID 17615799 · doi
• Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium.
  Thrombosis and haemostasis · 2007 · PMID 17938804
• Soluble CD40 ligand and interleukin-6 in the coronary circulation after acute myocardial infarction.
  International journal of cardiology · 2006 · PMID 16376442 · doi
• [Multi-biomarker approach to acute coronary syndrome].
  Nihon rinsho. Japanese journal of clinical medicine · 2006 · PMID 16613186
• Soluble CD40L levels are regulated by the -3459 A>G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST elevation acute coronary syndrome.
  Arteriosclerosis, thrombosis, and vascular biology · 2006 · PMID 16627810 · doi
• Serum osteoprotegerin in young survivors of myocardial infarction.
  Thrombosis and haemostasis · 2006 · PMID 16676081
• The potential role of antiplatelet agents in modulating inflammatory markers in atherothrombosis.
  Journal of thrombosis and haemostasis : JTH · 2006 · PMID 16961584 · doi
• Quest for novel cardiovascular biomarkers by proteomic analysis.
  Journal of proteome research · 2005 · PMID 16083268 · doi
• [Acute coronary syndrome and inflammation. Biomarkers for diagnostics and risk stratification].
  Herz · 2004 · PMID 15599673 · doi
• Hypercoagulability in sickle cell disease: a curious paradox.
  The American journal of medicine · 2003 · PMID 14693325 · doi
• Cardiopulmonary bypass induces release of soluble CD40 ligand.
  Circulation · 2002 · PMID 12070112 · doi
• CD40L activation in circulating platelets in patients with acute coronary syndrome.
  Cardiology · 1999 · PMID 10640791 · doi