enoyl-CoA hydratase domain-containing protein 3
ECHDC3geneMetabolic enzyme elevated in STEMI platelets with undefined role in platelet function.
Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencelow
RationaleElevated in STEMI platelets; metabolic enzyme role unclear in MI.
Druggability
DruggableYes
Known drugs / candidates0
Small-molecule tractableYes
Antibody tractableNo
EnsemblENSG00000134463
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood — gene is not a circulating analyte; measure protein product or genotype
Collection tube
K2-EDTA whole blood (lavender-top)
Method / principle
SNP genotyping / sequencing; or immunoassay of encoded protein
Reagent / substrate
Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein
Platform
qPCR / NGS / array
Turnaround · availability
Send-out · Genotyping widely available; protein assay variable
Literature evidence(1)
- Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction.Platelets · 2015 · PMID 26367242 · doi