Plasminogen

Assay & specimen

Human genetic evidence

Literature evidence(16)

• Oxidized phospholipids on plasminogen are associated with reduced platelet surface marker expression and intrinsic reactivity.
  Journal of thrombosis and thrombolysis · 2026 · PMID 41525016 · doi
• Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis.
  Cardiovascular therapeutics · 2025 · PMID 40026415 · doi
• Lipoprotein (a) in the context of atherosclerosis: pathological implications and therapeutic perspectives in myocardial infarction. A narrative review.
  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie · 2024 · PMID 39957022 · doi
• Differential effects of physiological agonists on the proteome of platelet-derived extracellular vesicles.
  Proteomics · 2024 · PMID 38556629 · doi
• Quantitative proteomics reveal three potential biomarkers for risk assessment of acute myocardial infarction.
  Bioengineered · 2022 · PMID 35156527 · doi
• Altered fibrin clot properties and fibrinolysis in patients with atrial fibrillation: practical implications.
  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2020 · PMID 31625555 · doi
• Increased von Willebrand factor, P-selectin and fibrin content in occlusive thrombus resistant to lytic therapy.
  Thrombosis and haemostasis · 2016 · PMID 26962963 · doi
• Altered plasma fibrin clot properties in essential thrombocythemia.
  Platelets · 2015 · PMID 25989112 · doi
• Characterization of the pro-thrombotic state in CAPD patients.
  Renal failure · 2008 · PMID 18661409 · doi
• Streptokinase-induced activation of the kallikrein-kinin system and of the contact phase in patients with acute myocardial infarction.
  Journal of cardiovascular pharmacology · 1998 · PMID 9593077 · doi
• Plasmin-mediated activation of contact system in response to pharmacological thrombolysis.
  Circulation · 1995 · PMID 7805216 · doi
• New recombinant glycosylated prourokinase for treatment of patients with acute myocardial infarction. Prourokinase Study Group.
  Journal of the American College of Cardiology · 1994 · PMID 7930246 · doi
• [Tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI)].
  Rinsho byori. The Japanese journal of clinical pathology · 1994 · PMID 8176842
• Fibrinolysis in patients with acute ischaemic heart disease. With particular reference to systemic effects of tissue-type plasminogen activator treatment on fibrinolysis, coagulation and complement pathways.
  Danish medical bulletin · 1993 · PMID 8222763
• [Biological manifestations of a prethrombotic state in developmental Crohn's disease].
  Gastroenterologie clinique et biologique · 1990 · PMID 2188861
• Fibrinolysis and plasminogen concentration in aortic intima in relation to death following myocardial infarction.
  Atherosclerosis · 1985 · PMID 4004989 · doi

Clinical trials(1)

• The Intracoronary Tissue-type Plasminogen Activator (t-PA) Release Predicts Major Adverse Cardiac Events in Patients With Non-critical Coronary Artery Disease
  NCT00868855 · PHASE1 · TERMINATED · Bradykinin