P-selectin

Type I vs Type II discrimination

Assay & specimen

Human genetic evidence

Literature evidence(60)

• Left atrial endocardial dysfunction and platelet activation in patients with atrial fibrillation and mitral stenosis.
  The Journal of thoracic and cardiovascular surgery · 2014 · PMID 24412254 · doi
• Collagen can selectively trigger a platelet secretory phenotype via glycoprotein VI.
  PloS one · 2014 · PMID 25116206 · doi
• Circulating markers of endothelial dysfunction and platelet activation in patients with severe symptomatic cerebral small vessel disease.
  Cerebrovascular diseases (Basel, Switzerland) · 2013 · PMID 24029712 · doi
• The association of ventricular tachycardia and endothelial dysfunction in the setting of acute myocardial infarction with ST elevation.
  Medical science monitor : international medical journal of experimental and clinical research · 2013 · PMID 24253420 · doi
• Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases.
  PloS one · 2012 · PMID 22624015 · doi
• Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target.
  Arteriosclerosis, thrombosis, and vascular biology · 2011 · PMID 21512161 · doi
• Epoprostenol inhibits human platelet-leukocyte mixed conjugate and platelet microparticle formation in whole blood.
  Thrombosis research · 2011 · PMID 21624644 · doi
• Platelet activation, coagulation activation and C-reactive protein in simultaneous samples from the vascular access and peripheral veins of haemodialysis patients.
  International journal of laboratory hematology · 2011 · PMID 21722325 · doi
• Soluble, platelet-bound, and total P-selectin as indices of platelet activation in congestive heart failure.
  Annals of medicine · 2009 · PMID 18618353 · doi
• Platelet turnover, coagulation factors, and soluble markers of platelet and endothelial activation in essential thrombocythemia: relationship with thrombosis occurrence and JAK2 V617F allele burden.
  American journal of hematology · 2009 · PMID 19105233 · doi
• Thrombin formation and platelet activation at the site of vascular injury in patients with coronary artery disease treated with clopidogrel combined with aspirin.
  Kardiologia polska · 2009 · PMID 19618315
• Platelet dense-granule secretion plays a critical role in thrombosis and subsequent vascular remodeling in atherosclerotic mice.
  Circulation · 2009 · PMID 19687360 · doi
• [P-selectin and its role in some diseases].
  Postepy higieny i medycyny doswiadczalnej (Online) · 2009 · PMID 19850970
• Platelet activation in patients with psoriasis: increased plasma levels of platelet-derived microparticles and soluble P-selectin.
  Journal of the American Academy of Dermatology · 2009 · PMID 19962788 · doi
• Human solCD39 inhibits injury-induced development of neointimal hyperplasia.
  Thrombosis and haemostasis · 2009 · PMID 20024507 · doi
• The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer.
  Biomaterials · 2009 · PMID 20042236 · doi
• Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice.
  The Journal of clinical investigation · 2008 · PMID 18431509 · doi
• Effects of von Willebrand factor concentration and platelet collision on shear-induced platelet activation.
  Thrombosis and haemostasis · 2008 · PMID 18612539 · doi
• Soluble P-selectin as a marker of in vivo platelet activation.
  Clinica chimica acta; international journal of clinical chemistry · 2008 · PMID 18835553 · doi
• Myocardial ischemic memory imaging with molecular echocardiography.
  Circulation · 2007 · PMID 17210843 · doi
• Platelet glycoprotein VI: a novel marker for acute coronary syndrome.
  Seminars in thrombosis and hemostasis · 2007 · PMID 17340467 · doi
• Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease.
  Vascular medicine (London, England) · 2007 · PMID 17615799 · doi
• Prothrombotic markers and early spontaneous recanalization in ST-segment elevation myocardial infarction.
  Thrombosis and haemostasis · 2007 · PMID 17721626
• Review of the pleiotropic effects of peroxisome proliferator-activated receptor gamma agonists on platelet function.
  Diabetes technology & therapeutics · 2007 · PMID 17931049 · doi
• Leukocyte adhesion and thrombosis.
  Current opinion in hematology · 2006 · PMID 16319685 · doi
• Heparin immobilization reduces thrombogenicity of small-caliber expanded polytetrafluoroethylene grafts.
  Journal of vascular surgery · 2006 · PMID 16520178 · doi
• Soluble guanylyl cyclase activation with HMR1766 attenuates platelet activation in diabetic rats.
  Arteriosclerosis, thrombosis, and vascular biology · 2006 · PMID 17023677 · doi
• Evaluation of markers of endothelial damage in cases of young myocardial infarction.
  Atherosclerosis · 2005 · PMID 15910865 · doi
• Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression.
  The American journal of psychiatry · 2005 · PMID 15932816 · doi
• The emerging value of P-selectin as a disease marker.
  Clinical chemistry and laboratory medicine · 2004 · PMID 15202782 · doi
• Platelet activation as a marker for in vivo prothrombotic activity: detection by flow cytometry.
  Journal of biological regulators and homeostatic agents · 2004 · PMID 15471223
• P-selectin in arterial thrombosis.
  Zeitschrift fur Kardiologie · 2004 · PMID 15568145 · doi
• Increased soluble platelet/endothelial cell adhesion molecule-1 in the early stages of acute coronary syndromes.
  International journal of cardiology · 2003 · PMID 12957760 · doi
• Enhanced platelet/endothelial activation in depressed patients with acute coronary syndromes: evidence from recent clinical trials.
  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis · 2003 · PMID 12960610 · doi
• The stratification of platelet reactivity and activation in patients with stable coronary artery disease on aspirin therapy.
  Thrombosis research · 2003 · PMID 15013266 · doi
• Increases in circulating levels of monocyte-platelet and neutrophil-platelet complexes following hip arthroplasty.
  Clinical science (London, England : 1979) · 2002 · PMID 11869168
• A reliable plasma marker of platelet activation: does it exist?
  American journal of hematology · 2002 · PMID 12111787 · doi
• Thrombogenesis in sickle cell disease.
  The Journal of laboratory and clinical medicine · 2001 · PMID 11385360 · doi
• Vascular adhesion protein-1, intercellular adhesion molecule-1 and P-selectin mediate leukocyte binding to ischemic heart in humans.
  Journal of the American College of Cardiology · 2000 · PMID 10898423 · doi
• A pilot study of streptokinase-induced endothelial injury and platelet activation following acute myocardial infarction.
  Journal of internal medicine · 2000 · PMID 11086642 · doi