ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST3GAL6proteinST3GAL6 regulates platelet adhesion molecule glycosylation, affecting platelet aggregation capacity.
Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencemedium
RationaleGlycosyltransferase modulating platelet surface receptor function.
Druggability
DruggableYes
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableYes
EnsemblENSG00000064225
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction.Platelets · 2015 · PMID 26367242 · doi