CD41+ microparticles
complexCD41+ microparticles reflect platelet activation and contribute to thrombin generation and thrombus formation post-plaque rupture.
Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencehigh
RationalePlatelet-derived microparticles; markers of platelet activation and procoagulant activity.
Also acts inCoagulation / thrombus
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Plasma (citrate for coagulation complexes)
Collection tube
Sodium citrate 3.2% (light blue-top) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich ELISA against neo-complex epitope
Reagent / substrate
Antibody pair recognizing the assembled complex
Platform
ELISA plate
Turnaround · availability
Research / send-out · Research/specialized
Literature evidence(1)
- Microparticles during long-term follow-up after acute myocardial infarction. Association to atherosclerotic burden and risk of cardiovascular events.Thrombosis and haemostasis · 2017 · PMID 28424820 · doi