D-dimer

Type I vs Type II discrimination

Assay & specimen

Literature evidence(60)

• Plasma fibrin clot properties in atopic dermatitis: links between thrombosis and atopy.
  Journal of thrombosis and thrombolysis · 2010 · PMID 20419337 · doi
• A timely diagnosis of myocardial infarction.
  Biomarkers in medicine · 2010 · PMID 20550472 · doi
• Evaluation of D-dimer in the diagnosis of suspected aortic dissection.
  Clinical chemistry and laboratory medicine · 2010 · PMID 20704542 · doi
• Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome.
  Thrombosis and haemostasis · 2010 · PMID 20806117 · doi
• Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men.
  Journal of thrombosis and haemostasis : JTH · 2009 · PMID 19682232 · doi
• Plasma soluble fibrin monomer complex as a marker of coronary thrombotic events in patients with acute myocardial infarction.
  The Tohoku journal of experimental medicine · 2009 · PMID 19713681 · doi
• Contribution of novel biomarkers to incident stable angina and acute coronary syndrome: the PRIME Study.
  European heart journal · 2008 · PMID 18621771 · doi
• Characterization of the pro-thrombotic state in CAPD patients.
  Renal failure · 2008 · PMID 18661409 · doi
• The prognostic utility of D-dimer and fibrin monomer at long-term follow-up after hospitalization with coronary chest pain.
  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis · 2008 · PMID 18832914 · doi
• Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischaemic events: observations from the ESTEEM Trial.
  European heart journal · 2007 · PMID 17314111 · doi
• Fibrinolysis in patients with an abdominal aortic aneurysm with special emphasis on rupture and shock.
  Journal of thrombosis and haemostasis : JTH · 2007 · PMID 17922806 · doi
• A multimarker risk stratification approach to non-ST elevation acute coronary syndrome: implications of troponin T, CRP, NT pro-BNP and fibrin D-dimer levels.
  Journal of internal medicine · 2007 · PMID 17986200 · doi
• Do plasma biomarkers of coagulation and fibrinolysis differ between patients who have experienced an acute myocardial infarction versus stable exertional angina?
  American heart journal · 2007 · PMID 18035075 · doi
• Assessment of markers of thrombin generation in patients with acute myocardial infarction complicated by ventricular fibrillation.
  Clinical cardiology · 2006 · PMID 16649726 · doi
• Plasma markers of activated hemostasis in the early diagnosis of acute coronary syndromes.
  Clinica chimica acta; international journal of clinical chemistry · 2006 · PMID 16696962 · doi
• Activated coagulation during open and endovascular abdominal aortic aneurysm repair.
  Journal of vascular surgery · 2006 · PMID 16765226 · doi
• Tissue plasminogen activator antigen is strongly associated with myocardial infarction in young women.
  Journal of thrombosis and haemostasis : JTH · 2005 · PMID 15670033 · doi
• Evaluation and management of the acutely dyspneic patient: the role of biomarkers.
  The American journal of emergency medicine · 2005 · PMID 15915417 · doi
• Tissue factor pathway inhibitor, natural coagulation inhibitors and hemostatic activation markers in patients with acute coronary syndromes.
  Saudi medical journal · 2005 · PMID 15983678
• Long-term treatment with ximelagatran, an oral direct thrombin inhibitor, persistently reduces the coagulation activity after a myocardial infarction.
  Journal of thrombosis and haemostasis : JTH · 2005 · PMID 16194202 · doi
• Association between early postoperative coagulation activation and peri-operative myocardial ischaemia in patients undergoing vascular surgery.
  Anaesthesia · 2005 · PMID 16288612 · doi
• Increased levels of soluble tissue factor during long-term treatment with warfarin in patients after an acute myocardial infarction.
  Journal of thrombosis and haemostasis : JTH · 2004 · PMID 15099277 · doi
• [Role of fibrin D-dimer in acute coronary syndrome. Prospective study of 22 cases].
  La Tunisie medicale · 2004 · PMID 15127704
• Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease.
  Arteriosclerosis, thrombosis, and vascular biology · 2004 · PMID 15205218 · doi
• A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C-reactive protein following myocardial infarction: the CADET trial.
  Journal of thrombosis and haemostasis : JTH · 2004 · PMID 15550024 · doi
• Coagulation indicators in chronic stable effort angina and unstable angina: relationship with acute phase reactants and clinical outcome.
  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis · 2002 · PMID 11943939 · doi
• Evaluation of coagulation markers for early diagnosis of acute coronary syndromes in the emergency room.
  Clinical chemistry · 2002 · PMID 12406977
• Procoagulant effects of thrombolytic therapy in acute myocardial infarction.
  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih · 2002 · PMID 12894883
• Factor V Leiden and its relation to left ventricular thrombus in acute myocardial infarction.
  Acta cardiologica · 2001 · PMID 11315119 · doi
• Thrombogenesis in sickle cell disease.
  The Journal of laboratory and clinical medicine · 2001 · PMID 11385360 · doi
• Coagulation activity and clinical outcome in unstable coronary artery disease.
  Arteriosclerosis, thrombosis, and vascular biology · 2001 · PMID 11397720 · doi
• Prognostic role of hemostatic markers in acute coronary syndromes patients.
  Clinica chimica acta; international journal of clinical chemistry · 2001 · PMID 11557250 · doi
• How to search for the role and prevalence of defective fibrinolytic states as triggers of myocardial infarction? The haemostasis epidemiologist's view.
  Italian heart journal : official journal of the Italian Federation of Cardiology · 2001 · PMID 11666092
• Fibrin specificity and procoagulant effect related to the kallikrein-contact phase system and to plasmin generation with double-bolus reteplase and front-loaded alteplase thrombolysis in acute myocardial infarction.
  The American journal of cardiology · 2000 · PMID 10922430 · doi
• Plasma levels of activated protein C-protein C inhibitor complex in patients with hypercoagulable states.
  American journal of hematology · 2000 · PMID 10936861 · doi
• Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial. OASIS Pilot Study Investigators. Organization to Assess Strategies for Ischemic++ Syndromes.
  European heart journal · 2000 · PMID 10952840 · doi
• D-Dimer is an early diagnostic marker of coronary ischemia in patients with chest pain.
  American heart journal · 2000 · PMID 10966534 · doi
• Early risk stratification of unstable angina/non-Q myocardial infarction: biochemical markers of coronary thrombosis.
  International journal of cardiology · 1999 · PMID 10328612 · doi
• [Blood coagulation and fibrinolysis in arteriosclerosis].
  Zeitschrift fur Kardiologie · 1999 · PMID 10413853 · doi
• Study on the hypercoagulable state in patients with angina and myocardial infarction.
  Journal of Tongji Medical University = Tong ji yi ke da xue xue bao · 1998 · PMID 10806795 · doi

Clinical trials(1)

• A Randomized Controlled Clinical Trial of PARIS Coronary Thrombosis Risk Score Combined With D-dimer to Guide New Oral Anticoagulant Antithrombotic Therapy in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention
  NCT05638867 · PHASE4 · RECRUITING · Aspirin + Clopidogrel + Rivaroxaban, Aspirin + Clopidogrel