Fragment D neoantigen

peptide

Neoepitope released during fibrinolytic degradation of cross-linked fibrin in coronary thrombus.

Pathway placement

Cascade stepCoagulation & thrombus formation

Confidencehigh

RationaleNeoepitope of fibrin cross-linking and degradation; hypercoagulability marker.

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Plasma (EDTA; peptidase-labile — chilled + protease inhibitor)

Collection tube

K2-EDTA, chilled plastic (lavender-top) · Serum separator (gold/red-top, SST)

Method / principle

Competitive/sandwich immunoassay or LC-MS/MS

Reagent / substrate

Anti-peptide antibody; or isotope-labeled internal standard (MS)

Platform

Immunoassay / LC-MS/MS

Turnaround · availability

Send-out / research · Research-grade