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Fragment E neoantigen
Pathway / Coagulation & thrombus formation

Fragment E neoantigen

peptide

Neoepitope released during fibrinolytic degradation indicating active thrombus formation and fibrin turnover.

Pathway placement
Cascade stepCoagulation & thrombus formation
Confidencehigh
RationaleNeoepitope of fibrin degradation; specific hypercoagulability and fibrinolysis marker.
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Plasma (EDTA; peptidase-labile — chilled + protease inhibitor)
Collection tube
K2-EDTA, chilled plastic (lavender-top) · Serum separator (gold/red-top, SST)
Method / principle
Competitive/sandwich immunoassay or LC-MS/MS
Reagent / substrate
Anti-peptide antibody; or isotope-labeled internal standard (MS)
Platform
Immunoassay / LC-MS/MS
Turnaround · availability
Send-out / research · Research-grade

Literature evidence(1)