FX-06
peptideFX-06 is a fibrin-derived peptide that mitigates ischemia-reperfusion injury following coronary thrombus resolution.
Pathway placement
Cascade stepCoagulation & thrombus formation
Confidencemedium
RationaleFibrin-derived peptide targeting reperfusion injury from thrombus lysis.
Also acts inMyocardial injury
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Plasma (EDTA; peptidase-labile — chilled + protease inhibitor)
Collection tube
K2-EDTA, chilled plastic (lavender-top) · Serum separator (gold/red-top, SST)
Method / principle
Competitive/sandwich immunoassay or LC-MS/MS
Reagent / substrate
Anti-peptide antibody; or isotope-labeled internal standard (MS)
Platform
Immunoassay / LC-MS/MS
Turnaround · availability
Send-out / research · Research-grade
Literature evidence(1)
- FX-06, a fibrin-derived Bbeta15-42 peptide for the potential treatment of reperfusion injury following myocardial infarction.Current opinion in investigational drugs (London, England : 2000) · 2009 · PMID 19705343