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Mean Platelet Volume
Pathway / Platelet adhesion & activation

Mean Platelet Volume

other

Mean platelet volume reflects platelet function and predicts thrombotic recurrence in acute coronary syndromes.

Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencemedium
RationalePlatelet size correlates with reactivity and thrombotic recurrence risk.
Also acts inCoagulation / thrombus
Druggability
Not assessed (no mapped human gene target).

Type I vs non-Type I discrimination

ScoresShared / rises in both
R — rupture / Type-I
67
C — non-Type-I
61
A — assay feasibility
45
E — evidence strength
86
T1DI (composite)
21
Specificity differential (R−C)+6.1
Non-Type-I axis panel
Does this marker also move in each non-Type-I setting? mag 0–3; higher means less Type-I-specific. n/a = no evidence retrieved, which is not the same as no change.
2sepsis / systemic inflammationmag 2
2anemia / acute blood lossmag 2
2hypovolemia / dehydrationmag 2
2tachyarrhythmiamag 2
2hypoxemia / respiratory failuremag 2
2hypertensive emergencymag 3
2high-demand / peri-operative stressmag 2
3sudden cardiac deathn/a
4aPCI-related periproceduralmag 1
4bstent thrombosismag 2
4cin-stent restenosismag 1
5CABG-relatedmag 1
Coverage: 11/12 axes with evidence
Tier: deep-scored (abstract-extracted) · 31 supporting references. See the discrimination table for all markers.

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST)
Method / principle
Method depends on analyte chemistry
Reagent / substrate
Analyte-specific
Platform
Variable
Turnaround · availability
Research · Research

Literature evidence(4)