miR-199a-3p
rnamiR-199a-3p is a circulating microRNA biomarker of platelet activation that regulates genes governing thromboinflammatory responses.
Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencemedium
RationalePlatelet activation biomarker; miRNA regulation of thrombotic pathways.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Comprehensive Characterization of Platelet-Enriched MicroRNAs as Biomarkers of Platelet Activation.Cells · 2022 · PMID 35455934 · doi