Myosin
proteinMyosin-driven actin sliding powers platelet contraction and thrombus compaction, enabling the transition from loose plug to stable occlusive clot.
Pathway placement
Cascade stepCoagulation & thrombus formation
Confidencemedium
RationaleActin motor; platelet contraction and thrombus compaction.
Also acts inPlatelet activation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Molecular signature of coronary stent thrombosis: oxidative stress and innate immunity cells.Thrombosis and haemostasis · 2017 · PMID 28640320 · doi