Platelet extracellular vesicles
otherPlatelet-derived extracellular vesicles released during activation amplify thrombin generation and fibrin formation, contributing to occlusive thrombus propagation in Type 1 MI.
Pathway placement
Cascade stepPlatelet adhesion & activation
Confidencehigh
RationalePlatelet activation marker; microvesicle-mediated thrombosis and coagulation.
Also acts inCoagulation / thrombus
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST)
Method / principle
Method depends on analyte chemistry
Reagent / substrate
Analyte-specific
Platform
Variable
Turnaround · availability
Research · Research
Literature evidence(1)
- Platelet extracellular vesicles as biomarkers for arterial thrombosis.Platelets · 2016 · PMID 27996341 · doi
Clinical trials(1)
- Antiplatelet Therapy Effect on Platelet Extracellular Vesicles in Acute Myocardial InfarctionNCT02931045 · PHASE4 · COMPLETED · Ticagrelor, Clopidogrel