Apolipoprotein F

APOFprotein

APOF modulates HDL-mediated lipid metabolism and LXR-pathway activation, affecting atherosclerotic lipid retention and post-MI remodeling.

Pathway placement

Cascade stepLipid retention & oxidation

Confidencemedium

RationaleHDL-associated apolipoprotein; LXR/RXR lipid-metabolism pathway; lipid-retention and metabolic-homeostasis axis.

Also acts inSystemic / off-pathway

Druggability

DruggableYes

Known drugs / candidates0

Small-molecule tractableNo

Antibody tractableYes

EnsemblENSG00000175336

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum or plasma

Collection tube

Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)

Method / principle

Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists

Reagent / substrate

Matched anti-target antibody pair (capture + labeled detection)

Platform

ELISA microplate or multiplex (Luminex/MSD)

Turnaround · availability

Send-out / research · Research-grade (no universal clinical assay)