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CD6
Pathway / Plaque inflammation

CD6

CD6protein

CD6 promotes T-cell recruitment and inflammatory activation in coronary atherosclerotic plaque.

Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleLymphocyte adhesion molecule; independent MI risk factor.
Also acts inPlatelet activation
Druggability
DruggableYes
Known drugs / candidates2
Small-molecule tractableNo
Antibody tractableYes
EnsemblENSG00000013725

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)

Literature evidence(1)