Cell Migration Inducing hyaluronan Binding Protein
CEMIPgeneCEMIP expression is induced during atherosclerotic plaque development and contributes to vascular inflammation and plaque progression.
Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleAtherosclerosis-induced gene with roles in vascular remodeling and inflammatory cell recruitment.
Also acts inLipid entry/oxidation
Druggability
DruggableYes
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableYes
EnsemblENSG00000103888
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood — gene is not a circulating analyte; measure protein product or genotype
Collection tube
K2-EDTA whole blood (lavender-top)
Method / principle
SNP genotyping / sequencing; or immunoassay of encoded protein
Reagent / substrate
Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein
Platform
qPCR / NGS / array
Turnaround · availability
Send-out · Genotyping widely available; protein assay variable
Literature evidence(1)
- Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis.Cardiovascular research · 2024 · PMID 38289873 · doi