CoronaryAtlas logo
CoronaryAtlas
C-X-C motif chemokine ligand-like factor 1
Pathway / Plaque inflammation

C-X-C motif chemokine ligand-like factor 1

CKLF1protein

CKLF1 drives monocyte chemotaxis and plaque inflammation, destabilizing atherosclerotic lesions prior to rupture.

Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleChemokine mediating monocyte recruitment and leukocyte infiltration in atherosclerotic plaques.
Also acts inPlatelet activation
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)

Literature evidence(1)