CLEC4D
CLEC4DproteinCLEC4D is a core gene shared between ischemic stroke and MI; regulates myeloid-cell activation and inflammatory responses in atherothrombosis.
Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleCLEC4D is a C-type lectin receptor modulating leukocyte and platelet activation in inflammation.
Also acts inPlatelet activation
Druggability
DruggableYes
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableYes
EnsemblENSG00000166527
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Identification of core genes shared by ischemic stroke and myocardial infarction using an integrated approach.Medicine · 2024 · PMID 38968466 · doi