Coronin-1A
CORO1AproteinCoronin-1A reflects myocardial electrical instability and sudden death risk, separate from atherothrombotic pathway.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleActin-regulating protein; associates with sudden cardiac death risk, off-pathway mechanism.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Novel Protein-Based Biomarkers of Out-of-hospital Sudden Cardiac Death After Myocardial Infarction.Circulation. Arrhythmia and electrophysiology · 2025 · PMID 40143805 · doi