Cysteine and glycine-rich protein 3
CSRP3proteinCSRP3 is a cardiac-restricted protein released upon cardiomyocyte injury and serves as an early MI damage marker.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencehigh
RationaleCardiac-specific mechanotransduction protein released during myocardial necrosis.
Druggability
DruggableNo
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableNo
EnsemblENSG00000129170
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Application of Large-Scale Aptamer-Based Proteomic Profiling to Planned Myocardial Infarctions.Circulation · 2017 · PMID 29222138 · doi