HECW2

HECW2gene

HECW2 is elevated in acute coronary syndrome but its specific role in atherothrombotic pathophysiology remains to be defined.

Pathway placement

Cascade stepMyocardial injury (shared endpoint)

Confidencelow

RationaleIdentified as ACS biomarker; mechanism in MI/ACS not yet mechanistically mapped to atherothrombotic cascade.

Druggability

DruggableNo

Known drugs / candidates0

Small-molecule tractableNo

Antibody tractableNo

EnsemblENSG00000138411

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Whole blood — gene is not a circulating analyte; measure protein product or genotype

Collection tube

K2-EDTA whole blood (lavender-top)

Method / principle

SNP genotyping / sequencing; or immunoassay of encoded protein

Reagent / substrate

Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein

Platform

qPCR / NGS / array

Turnaround · availability

Send-out · Genotyping widely available; protein assay variable