Kruppel Like Factor 14

KLF14gene

KLF14 regulates lipid metabolism and ApoB-lipoprotein processing, modulating substrate for atherogenesis.

Pathway placement

Cascade stepLipid retention & oxidation

Confidencehigh

RationaleTranscriptional regulator of lipoprotein metabolism and atherosclerosis risk.

Druggability

DruggableNo

Known drugs / candidates0

Small-molecule tractableNo

Antibody tractableNo

EnsemblENSG00000266265

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Whole blood — gene is not a circulating analyte; measure protein product or genotype

Collection tube

K2-EDTA whole blood (lavender-top)

Method / principle

SNP genotyping / sequencing; or immunoassay of encoded protein

Reagent / substrate

Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein

Platform

qPCR / NGS / array

Turnaround · availability

Send-out · Genotyping widely available; protein assay variable