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microRNA-134-5p
Pathway / Myocardial injury (shared endpoint)

microRNA-134-5p

MIR134rna

Circulating miR-134-5p released from ischemic myocardium serves as an early diagnostic biomarker for STEMI.

Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationaleCirculating miRNA diagnostic marker detectable early in STEMI, reflects cardiomyocyte damage.
Also acts inVascular inflammation
Druggability
DruggableNo
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableNo
EnsemblENSG00000207993

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)

Literature evidence(1)