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microRNA-181a
Pathway / Myocardial injury (shared endpoint)

microRNA-181a

MIR181A1rna

Circulating miR-181a reflects myocardial necrosis and inflammatory response in acute MI.

Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationaleCirculating miRNA biomarker released during acute myocardial infarction and cardiomyocyte damage.
Also acts inVascular inflammation
Druggability
DruggableNo
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableNo
EnsemblENSG00000207759

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)

Literature evidence(1)