Polyhomeotic Chromodomain-like Protein 2 (PHC2 / EDR1)

PHC2gene

PHC2 expression dysregulation modulates immune cell activation in acute MI inflammation.

Pathway placement

Cascade stepPlaque inflammation

Confidencelow

RationaleChromatin regulator linked to immune cell differentiation and inflammatory responses.

Druggability

DruggableNo

Known drugs / candidates0

Small-molecule tractableNo

Antibody tractableNo

EnsemblENSG00000134686

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Whole blood — gene is not a circulating analyte; measure protein product or genotype

Collection tube

K2-EDTA whole blood (lavender-top)

Method / principle

SNP genotyping / sequencing; or immunoassay of encoded protein

Reagent / substrate

Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein

Platform

qPCR / NGS / array

Turnaround · availability

Send-out · Genotyping widely available; protein assay variable