Protein phosphatase 2 regulatory subunit 3A
PPP2R3AproteinPPP2R3A modulates phosphatase activity in inflammatory pathways implicated in coronary atherothrombotic disease.
Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationalePhosphatase regulating inflammatory signaling; CAD/MI drug target.
Druggability
DruggableNo
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableNo
EnsemblENSG00000073711
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Human genetic evidence
1
GWAS associations
Traits: myocardial infarction
Literature evidence(1)
- Druggability of Coronary Artery Disease Risk Loci.Circulation. Genomic and precision medicine · 2018 · PMID 30354342 · doi