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Proteasome subunit alpha 6
Pathway / Off-pathway / systemic markers

Proteasome subunit alpha 6

PSMA6protein

PSMA6 is a MI susceptibility locus, plausibly linked to proteasomal regulation of inflammatory or cell-cycle signaling.

Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleMI susceptibility locus; proteasomal function; off-pathway generic protein turnover marker.
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)

Literature evidence(2)