RNAS6
RNAS6proteinRNAS6 participates in vascular inflammation and fibrotic remodeling associated with atherosclerotic plaque progression.
Pathway placement
Cascade stepPlaque inflammation
Confidencelow
RationaleRoles in fibrosis and vascular inflammation; mechanism in atherosclerotic plaque destabilization less defined.
Also acts inCap degradation / rupture
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Proteogenomic Analysis of Coronary Artery Calcification in Human Populations.Arteriosclerosis, thrombosis, and vascular biology · 2026 · PMID 41924874 · doi