Sodium/Myo-Inositol Cotransporter 1
SLC5A3geneSLC5A3 (SMIT1) expression reflects myocardial metabolic dysregulation in heart-failure pathophysiology.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleInositol transporter; heart-failure marker not directly related to atherothrombotic Type 1 MI cascade.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood — gene is not a circulating analyte; measure protein product or genotype
Collection tube
K2-EDTA whole blood (lavender-top)
Method / principle
SNP genotyping / sequencing; or immunoassay of encoded protein
Reagent / substrate
Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein
Platform
qPCR / NGS / array
Turnaround · availability
Send-out · Genotyping widely available; protein assay variable