CoronaryAtlas logo
CoronaryAtlas
SLIT1
Pathway / Off-pathway / systemic markers

SLIT1

SLIT1gene

SLIT1 is a protective gene associated with supernormal coronary-artery phenotype; acts via developmental vascular-guidance pathways independent of atherothrombosis.

Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleSupernormal coronary phenotype; developmental guidance; protective, off-pathway.
Also acts inEndothelial activation/erosion
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood — gene is not a circulating analyte; measure protein product or genotype
Collection tube
K2-EDTA whole blood (lavender-top)
Method / principle
SNP genotyping / sequencing; or immunoassay of encoded protein
Reagent / substrate
Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein
Platform
qPCR / NGS / array
Turnaround · availability
Send-out · Genotyping widely available; protein assay variable

Literature evidence(1)