Small Nucleolar RNA Host Gene 7
SNHG7rnaSNHG7 regulates inflammatory pathways and myocardial remodeling relevant to acute coronary syndrome progression.
Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleLong non-coding RNA with roles in inflammatory response and cardiac remodeling post-MI.
Also acts inMyocardial injury
Druggability
DruggableNo
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableNo
EnsemblENSG00000233016
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood (transcript)
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Long non-coding RNA SNHG7 serves as a diagnostic biomarker for acute coronary syndrome and its predictive value for the clinical outcome after percutaneous coronary intervention.Journal of cardiothoracic surgery · 2024 · PMID 39014478 · doi