Steroidogenic acute regulatory protein
STARD1proteinSTARD1-mediated cholesterol transport regulates steroid synthesis and may indirectly influence lipid metabolism in atherosclerosis.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleMitochondrial cholesterol transport; steroidogenic regulation; metabolic axis.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Peroxidized cholesterol in low density lipoprotein: Negative effects on human endothelial cells and atherogenic implications.Archives of biochemistry and biophysics · 2026 · PMID 42270057 · doi