Tubulin beta 8 class IV
TUBB8geneTissue-specific cytoskeletal tubulin; unrelated to atherothrombosis.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleTestis-enriched microtubule protein; no atherothrombotic mechanism.
Druggability
DruggableYes
Known drugs / candidates88
Small-molecule tractableYes
Antibody tractableNo
EnsemblENSG00000261456
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood — gene is not a circulating analyte; measure protein product or genotype
Collection tube
K2-EDTA whole blood (lavender-top)
Method / principle
SNP genotyping / sequencing; or immunoassay of encoded protein
Reagent / substrate
Allele-specific primers/probes (TaqMan) or NGS panel; or antibody for protein
Platform
qPCR / NGS / array
Turnaround · availability
Send-out · Genotyping widely available; protein assay variable
Human genetic evidence
0.563
Open Targets association (myocardial_infarction)
Literature evidence(0)
No direct literature mentions harvested; included via genetic/target evidence.