Lymphotactin (XCL1)
XCL1proteinChemokine mediating lymphocyte recruitment in plaque inflammation and post-MI ventricular remodeling.
Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleLymphocyte-recruiting chemokine; LV dilation association suggests plaque-inflammation and remodeling response.
Also acts inSystemic / off-pathway
Druggability
DruggableYes
Known drugs / candidates0
Small-molecule tractableNo
Antibody tractableYes
EnsemblENSG00000143184
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction.Biochimica et biophysica acta. Molecular basis of disease · 2018 · PMID 31109452 · doi