11-dehydrothromboxane B2

metabolite

11-dehydrothromboxane B2 is the stable metabolite of thromboxane A2, marking COX-1-driven platelet activation and recruitment.

Pathway placement

Cascade stepThromboxane amplification

Confidencehigh

RationaleAnchor marker of thromboxane A2 generation and platelet activation.

Also acts inPlatelet activation

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum, plasma or urine

Collection tube

Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container

Method / principle

LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available

Reagent / substrate

Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent

Platform

LC-MS/MS; some automated chemistry

Turnaround · availability

Send-out / research · Specialized / research