12(S)-HPETE

lipid

Lipoxygenase metabolite amplifying inflammation and oxidative stress in acute myocardial infarction.

Pathway placement

Cascade stepPlaque inflammation

Confidencehigh

RationaleLipoxygenase lipid mediator driving inflammatory and oxidative responses in AMI.

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum or plasma (EDTA to limit oxidation)

Collection tube

K2/K3-EDTA (lavender-top) · Serum separator (gold/red-top, SST)

Method / principle

LC-MS/MS lipidomics (targeted or shotgun)

Reagent / substrate

Deuterated lipid-class internal standards; MS/MS transitions

Platform

LC-MS/MS

Turnaround · availability

Research · Research-only