20-HETE ethanolamide
metabolite20-HETE ethanolamide is an eicosanoid metabolite associated with lipid peroxidation and acute myocardial injury.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencemedium
RationaleEicosanoid biomarker in AMI; reflects lipid mediator dysregulation.
Also acts inLipid entry/oxidation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research
Literature evidence(1)
- Integrated oral microbiome and metabolome analysis unveils key biomarkers and functional pathway alterations in patients with acute myocardial infarction.Frontiers in cellular and infection microbiology · 2025 · PMID 40822584 · doi