2-Hydroxybutyric acid

metabolite

2-Hydroxybutyrate, an abnormal fatty-acid oxidation product, marks myocardial ischemic metabolic dysfunction in early acute coronary syndromes.

Pathway placement

Cascade stepOff-pathway / systemic markers

Confidencemedium

RationaleFatty-acid oxidation metabolite; ischemic metabolic stress and myocardial energy depletion marker.

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum, plasma or urine

Collection tube

Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container

Method / principle

LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available

Reagent / substrate

Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent

Platform

LC-MS/MS; some automated chemistry

Turnaround · availability

Send-out / research · Specialized / research