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8,9-DiHETrE
Pathway / Plaque inflammation

8,9-DiHETrE

metabolite

Oxylipin inflammatory mediator associated with plaque inflammation and cardiovascular thrombotic events.

Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleOxylipin metabolite; lipid mediator of inflammation associated with cardiovascular events.
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research

Literature evidence(1)