Anti-oxidized LDL antibodies
proteinAnti-oxLDL antibodies reflect the extent of lipoprotein oxidative modification, a key atherogenic signal in subendothelial lipid retention.
Pathway placement
Cascade stepLipid retention & oxidation
Confidencehigh
RationaleImmune response to oxidized LDL; marker of oxidative lipoprotein modification.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Oxidized LDL and anti-oxidized LDL antibodies in atherosclerosis - Novel insights and future directions in diagnosis and therapy<sup/>.Trends in cardiovascular medicine · 2018 · PMID 29934015 · doi