Bbeta15-42
peptideBbeta15-42 is a fibrin-derived peptide that exerts anti-inflammatory and cardioprotective effects during reperfusion injury after MI.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencemedium
RationaleFibrin-derived peptide; anti-inflammatory repair signaling post-reperfusion.
Also acts inMyocardial injury
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Plasma (EDTA; peptidase-labile — chilled + protease inhibitor)
Collection tube
K2-EDTA, chilled plastic (lavender-top) · Serum separator (gold/red-top, SST)
Method / principle
Competitive/sandwich immunoassay or LC-MS/MS
Reagent / substrate
Anti-peptide antibody; or isotope-labeled internal standard (MS)
Platform
Immunoassay / LC-MS/MS
Turnaround · availability
Send-out / research · Research-grade
Literature evidence(1)
- The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia-reperfusion injury.Nature medicine · 2005 · PMID 15723073 · doi