C-C Motif Chemokine Ligand 21

protein

CCL21 recruits lymphocytes and monocytes to the atherosclerotic lesion, amplifying plaque inflammation.

Pathway placement

Cascade stepPlaque inflammation

Confidencehigh

RationaleChemokine driving leukocyte recruitment in atherosclerotic plaque inflammation.

Also acts inPlatelet activation

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum or plasma

Collection tube

Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)

Method / principle

Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists

Reagent / substrate

Matched anti-target antibody pair (capture + labeled detection)

Platform

ELISA microplate or multiplex (Luminex/MSD)

Turnaround · availability

Send-out / research · Research-grade (no universal clinical assay)