Campesterol
metaboliteCampesterol, a plant sterol, is elevated in CAD/MI and reflects altered lipid metabolism and atherogenic lipid retention.
Pathway placement
Cascade stepLipid retention & oxidation
Confidencemedium
RationalePlant sterol biomarker for CAD/MI risk; reflects lipid metabolism and retention pathway.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research
Literature evidence(2)
- Genotype-based "virtual" metabolomics in a clinical biobank identifies novel metabolite-disease associations.Frontiers in genetics · 2024 · PMID 38812968 · doi
- Genotype-based "virtual" metabolomics in a clinical biobank identifies novel metabolite-disease associations.Research square · 2023 · PMID 37790512 · doi