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ceramide C24:1/C24:0
Pathway / Plaque inflammation

ceramide C24:1/C24:0

lipid

Ceramide C24:1/C24:0 is a pro-inflammatory sphingolipid that activates endothelial dysfunction and vascular inflammation, contributing to atherosclerotic plaque complexity and thrombotic risk.

Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleSphingolipid; promotes endothelial dysfunction and vascular inflammation.
Also acts inLipid entry/oxidation
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma (EDTA to limit oxidation)
Collection tube
K2/K3-EDTA (lavender-top) · Serum separator (gold/red-top, SST)
Method / principle
LC-MS/MS lipidomics (targeted or shotgun)
Reagent / substrate
Deuterated lipid-class internal standards; MS/MS transitions
Platform
LC-MS/MS
Turnaround · availability
Research · Research-only

Literature evidence(1)