Crosslinked fibrin degradation products
proteinCrosslinked fibrin degradation products reflect Factor XIII-stabilized thrombus formation and endogenous fibrinolytic activation.
Pathway placement
Cascade stepCoagulation & thrombus formation
Confidencehigh
RationaleCross-linked products indicate Factor XIII-stabilized fibrin and fibrinolytic turnover.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Fibrin metabolism in patients with acute myocardial infarction during and after treatment with tissue-type plasminogen activator.Thrombosis and haemostasis · 1988 · PMID 2976994