DNA-myeloperoxidase complexes
otherDNA-MPO complexes released by activated neutrophils form prothrombotic nets that amplify both plaque inflammation and thrombotic responses in Type 1 MI.
Pathway placement
Cascade stepPlaque inflammation
Confidencehigh
RationaleNeutrophil extracellular trap marker; NET-driven inflammation and thrombosis.
Also acts inPlatelet activation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST)
Method / principle
Method depends on analyte chemistry
Reagent / substrate
Analyte-specific
Platform
Variable
Turnaround · availability
Research · Research
Literature evidence(1)
- Circulating Extracellular DNA: Cause or Consequence of Thrombosis?Seminars in thrombosis and hemostasis · 2017 · PMID 28359134 · doi