ENST00000416860.2
rnaCirculating lncRNA dysregulated in acute myocardial infarction; precise mechanistic role in atherothrombotic cascade undefined.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencelow
RationalelncRNA dysregulated in acute MI; specific mechanism unclear but injury-associated.
Also acts inVascular inflammation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood (transcript)
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Expression pattern of genome-scale long noncoding RNA following acute myocardial infarction in Chinese Uyghur patients.Oncotarget · 2017 · PMID 28418905 · doi