Ganglioside GM3

lipid

GM3 ganglioside modulates immune cell and platelet activation during atherosclerotic plaque inflammation and thrombotic responses.

Pathway placement

Cascade stepPlaque inflammation

Confidencelow

RationaleGanglioside modulates immune cell activation in atherosclerotic lesions.

Also acts inPlatelet activation

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum or plasma (EDTA to limit oxidation)

Collection tube

K2/K3-EDTA (lavender-top) · Serum separator (gold/red-top, SST)

Method / principle

LC-MS/MS lipidomics (targeted or shotgun)

Reagent / substrate

Deuterated lipid-class internal standards; MS/MS transitions

Platform

LC-MS/MS

Turnaround · availability

Research · Research-only